F28L (p.Phe28Leu) variant of CDK6 (Cyclin-dependent kinase 6)
F28L (p.Phe28Leu) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
F28L (p.Phe28Leu) variant details
- p.Phe28Leu
- Ensembl rs2116033632
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- REVEL 0.41
- MetaLR 0.22
- MetaSVM -0.62
- CADD 26.50
- PolyPhen-2 0.35
- SIFT 0.01
- Population evidence available
- Structural context available