E18G (p.Glu18Gly) variant of CDK6 (Cyclin-dependent kinase 6)
E18G (p.Glu18Gly) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
E18G (p.Glu18Gly) variant details
- p.Glu18Gly
- Ensembl rs2116034185
- Missense
- Variant Prioritization Score for Impact Estimate 0.63
- REVEL 0.69
- MetaLR 0.42
- MetaSVM -0.13
- CADD 26.90
- PolyPhen-2 1.00
- SIFT 0.11
- Population evidence available
- Structural context available