D4E (p.Asp4Glu) variant of CDK6 (Cyclin-dependent kinase 6)
D4E (p.Asp4Glu) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
D4E (p.Asp4Glu) variant details
- p.Asp4Glu
- TOPMed rs937148501
- gnomAD rs937148501
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.07
- MetaLR 0.18
- MetaSVM -0.73
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.33
- Population evidence available
- Structural context available