A30S (p.Ala30Ser) variant of CDK6 (Cyclin-dependent kinase 6)
A30S (p.Ala30Ser) in CDK6 (Cyclin-dependent kinase 6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
A30S (p.Ala30Ser) variant details
- p.Ala30Ser
- Ensembl rs2116033525
- Missense
- Variant Prioritization Score for Impact Estimate 0.538
- REVEL 0.42
- MetaLR 0.32
- MetaSVM -0.36
- CADD 28.40
- PolyPhen-2 0.96
- SIFT 0.00
- Population evidence available
- Structural context available