Y77H (p.Tyr77His) variant of CDK2 (Cyclin-dependent kinase 2)
Y77H (p.Tyr77His) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
Y77H (p.Tyr77His) variant details
- p.Tyr77His
- gnomAD rs1325392225
- Missense
- Variant Prioritization Score for Impact Estimate 0.652
- REVEL 0.64
- CADD 29.20
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available