Y107H (p.Tyr107His) variant of CDK2 (Cyclin-dependent kinase 2)
Y107H (p.Tyr107His) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
Y107H (p.Tyr107His) variant details
- p.Tyr107His
- ExAC rs777345603
- gnomAD rs777345603
- Missense
- Variant Prioritization Score for Impact Estimate 0.734
- REVEL 0.80
- CADD 27.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available