Y107C (p.Tyr107Cys) variant of CDK2 (Cyclin-dependent kinase 2)
Y107C (p.Tyr107Cys) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
Y107C (p.Tyr107Cys) variant details
- p.Tyr107Cys
- gnomAD 12-55968782-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.611
- REVEL 0.73
- AlphaMissense 0.08
- MetaLR 0.00
- MetaSVM -1.04
- CADD 28.50
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available