V18A (p.Val18Ala) variant of CDK2 (Cyclin-dependent kinase 2)
V18A (p.Val18Ala) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
V18A (p.Val18Ala) variant details
- p.Val18Ala
- ExAC rs754042510
- gnomAD rs754042510
- Missense
- Variant Prioritization Score for Impact Estimate 0.73
- REVEL 0.77
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available