S120Y (p.Ser120Tyr) variant of CDK2 (Cyclin-dependent kinase 2)
S120Y (p.Ser120Tyr) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
S120Y (p.Ser120Tyr) variant details
- p.Ser120Tyr
- gnomAD 12-55968821-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.587
- REVEL 0.57
- AlphaMissense 0.28
- MetaLR 0.13
- MetaSVM -0.95
- CADD 25.60
- PolyPhen-2 0.84
- Population evidence available
- Structural context available
- Literature evidence available