R50G (p.Arg50Gly) variant of CDK2 (Cyclin-dependent kinase 2)
R50G (p.Arg50Gly) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
R50G (p.Arg50Gly) variant details
- p.Arg50Gly
- gnomAD 12-55967888-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.573
- REVEL 0.65
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available