R22K (p.Arg22Lys) variant of CDK2 (Cyclin-dependent kinase 2)
R22K (p.Arg22Lys) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
R22K (p.Arg22Lys) variant details
- p.Arg22Lys
- Ensembl rs1889336965
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.05
- CADD 19.30
- PolyPhen-2 0.00
- SIFT 0.63
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available