Q85E (p.Gln85Glu) variant of CDK2 (Cyclin-dependent kinase 2)
Q85E (p.Gln85Glu) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
Q85E (p.Gln85Glu) variant details
- p.Gln85Glu
- ExAC rs747703071
- gnomAD rs747703071
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.09
- CADD 21.30
- PolyPhen-2 0.38
- SIFT 0.27
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available