L96V (p.Leu96Val) variant of CDK2 (Cyclin-dependent kinase 2)
L96V (p.Leu96Val) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
L96V (p.Leu96Val) variant details
- p.Leu96Val
- ExAC rs746422426
- gnomAD rs746422426
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.08
- CADD 14.70
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the Ashkenazi Jewish population (allele frequency 0.00029)
- Structural context available