L96F (p.Leu96Phe) variant of CDK2 (Cyclin-dependent kinase 2)
L96F (p.Leu96Phe) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
L96F (p.Leu96Phe) variant details
- p.Leu96Phe
- gnomAD 12-55968140-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.05
- CADD 20.60
- PolyPhen-2 0.04
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available