L78V (p.Leu78Val) variant of CDK2 (Cyclin-dependent kinase 2)
L78V (p.Leu78Val) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
L78V (p.Leu78Val) variant details
- p.Leu78Val
- gnomAD 12-55968086-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.365
- REVEL 0.35
- CADD 23.20
- PolyPhen-2 0.73
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available