L115P (p.Leu115Pro) variant of CDK2 (Cyclin-dependent kinase 2)
L115P (p.Leu115Pro) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
L115P (p.Leu115Pro) variant details
- p.Leu115Pro
- gnomAD 12-55968806-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.716
- REVEL 0.91
- AlphaMissense 0.12
- MetaLR 0.14
- MetaSVM -0.87
- CADD 29.30
- PolyPhen-2 0.97
- Population evidence available
- Structural context available
- Literature evidence available