L103I (p.Leu103Ile) variant of CDK2 (Cyclin-dependent kinase 2)
L103I (p.Leu103Ile) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
L103I (p.Leu103Ile) variant details
- p.Leu103Ile
- gnomAD 12-55968161-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.14
- CADD 23.30
- PolyPhen-2 0.68
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available