K65T (p.Lys65Thr) variant of CDK2 (Cyclin-dependent kinase 2)
K65T (p.Lys65Thr) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
K65T (p.Lys65Thr) variant details
- p.Lys65Thr
- ExAC rs779522936
- TOPMed rs779522936
- gnomAD rs779522936
- Missense
- Variant Prioritization Score for Impact Estimate 0.365
- REVEL 0.19
- CADD 24.10
- PolyPhen-2 0.28
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available