K20N (p.Lys20Asn) variant of CDK2 (Cyclin-dependent kinase 2)
K20N (p.Lys20Asn) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
K20N (p.Lys20Asn) variant details
- p.Lys20Asn
- gnomAD 12-55967068-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.56
- REVEL 0.67
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available