K105E (p.Lys105Glu) variant of CDK2 (Cyclin-dependent kinase 2)
K105E (p.Lys105Glu) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
K105E (p.Lys105Glu) variant details
- p.Lys105Glu
- gnomAD 12-55968167-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.583
- REVEL 0.51
- CADD 29.80
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available