I104V (p.Ile104Val) variant of CDK2 (Cyclin-dependent kinase 2)
I104V (p.Ile104Val) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
I104V (p.Ile104Val) variant details
- p.Ile104Val
- gnomAD rs1261658227
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- REVEL 0.11
- CADD 17.90
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available