H121P (p.His121Pro) variant of CDK2 (Cyclin-dependent kinase 2)
H121P (p.His121Pro) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
H121P (p.His121Pro) variant details
- p.His121Pro
- gnomAD 12-55968824-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.64
- REVEL 0.64
- CADD 26.30
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available
- Literature evidence available