G98D (p.Gly98Asp) variant of CDK2 (Cyclin-dependent kinase 2)
G98D (p.Gly98Asp) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
G98D (p.Gly98Asp) variant details
- p.Gly98Asp
- gnomAD 12-55968147-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.31
- CADD 24.50
- PolyPhen-2 0.80
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available