G114S (p.Gly114Ser) variant of CDK2 (Cyclin-dependent kinase 2)
G114S (p.Gly114Ser) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
G114S (p.Gly114Ser) variant details
- p.Gly114Ser
- gnomAD 12-55968802-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.705
- REVEL 0.64
- CADD 28.40
- PolyPhen-2 0.98
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available