G114D (p.Gly114Asp) variant of CDK2 (Cyclin-dependent kinase 2)
G114D (p.Gly114Asp) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data, published literature, and structural context.
G114D (p.Gly114Asp) variant details
- p.Gly114Asp
- gnomAD 12-55968803-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.732
- REVEL 0.69
- CADD 27.20
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available