F117L (p.Phe117Leu) variant of CDK2 (Cyclin-dependent kinase 2)
F117L (p.Phe117Leu) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
F117L (p.Phe117Leu) variant details
- p.Phe117Leu
- gnomAD 12-55968811-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.655
- REVEL 0.66
- CADD 28.30
- PolyPhen-2 0.71
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available