F117I (p.Phe117Ile) variant of CDK2 (Cyclin-dependent kinase 2)
F117I (p.Phe117Ile) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
F117I (p.Phe117Ile) variant details
- p.Phe117Ile
- TOPMed rs1157590519
- gnomAD rs1157590519
- Missense
- Variant Prioritization Score for Impact Estimate 0.655
- REVEL 0.66
- CADD 28.00
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.00079)
- Structural context available