E42D (p.Glu42Asp) variant of CDK2 (Cyclin-dependent kinase 2)
E42D (p.Glu42Asp) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
E42D (p.Glu42Asp) variant details
- p.Glu42Asp
- gnomAD 12-55967866-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.30
- CADD 24.70
- PolyPhen-2 1.00
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available