D68Y (p.Asp68Tyr) variant of CDK2 (Cyclin-dependent kinase 2)
D68Y (p.Asp68Tyr) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data, published literature, and structural context.
D68Y (p.Asp68Tyr) variant details
- p.Asp68Tyr
- gnomAD 12-55968056-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.759
- REVEL 0.70
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available