D68V (p.Asp68Val) variant of CDK2 (Cyclin-dependent kinase 2)
D68V (p.Asp68Val) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data, published literature, and structural context.
D68V (p.Asp68Val) variant details
- p.Asp68Val
- gnomAD 12-55968057-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.727
- REVEL 0.76
- CADD 32.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available