A95T (p.Ala95Thr) variant of CDK2 (Cyclin-dependent kinase 2)
A95T (p.Ala95Thr) in CDK2 (Cyclin-dependent kinase 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
A95T (p.Ala95Thr) variant details
- p.Ala95Thr
- gnomAD 12-55968137-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.11
- CADD 19.10
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available