S40S (p.Ser40Ser) variant of CDK12 (Cyclin-dependent kinase 12)
S40S (p.Ser40Ser) in CDK12 (Cyclin-dependent kinase 12) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
S40S (p.Ser40Ser) variant details
- p.Ser40Ser
- gnomAD 17-39462191-G-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.458
- CADD 14.40
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available