S14R (p.Ser14Arg) variant of CDK12 (Cyclin-dependent kinase 12)
S14R (p.Ser14Arg) in CDK12 (Cyclin-dependent kinase 12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
S14R (p.Ser14Arg) variant details
- p.Ser14Arg
- TOPMed rs2048999631
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.20
- CADD 23.40
- PolyPhen-2 0.93
- SIFT 0.16
- Population evidence available
- Structural context available