G9S (p.Gly9Ser) variant of CDK12 (Cyclin-dependent kinase 12)
G9S (p.Gly9Ser) in CDK12 (Cyclin-dependent kinase 12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
G9S (p.Gly9Ser) variant details
- p.Gly9Ser
- gnomAD 17-39462096-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.18
- CADD 22.20
- PolyPhen-2 0.43
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available