G28D (p.Gly28Asp) variant of CDK12 (Cyclin-dependent kinase 12)
G28D (p.Gly28Asp) in CDK12 (Cyclin-dependent kinase 12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
G28D (p.Gly28Asp) variant details
- p.Gly28Asp
- TOPMed rs988490441
- Missense
- Variant Prioritization Score for Impact Estimate 0.488
- REVEL 0.28
- CADD 27.90
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available