G27V (p.Gly27Val) variant of CDK12 (Cyclin-dependent kinase 12)
G27V (p.Gly27Val) in CDK12 (Cyclin-dependent kinase 12) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
G27V (p.Gly27Val) variant details
- p.Gly27Val
- gnomAD 17-39462151-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.20
- CADD 27.30
- PolyPhen-2 1.00
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available