P25T (p.Pro25Thr) variant of CDH1 (Cadherin-1)
P25T (p.Pro25Thr) in CDH1 (Cadherin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
P25T (p.Pro25Thr) variant details
- p.Pro25Thr
- rs1454715253
- gnomAD 19-3523053-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.16
- MetaLR 0.04
- MetaSVM -1.09
- CADD 22.00
- PolyPhen-2 0.00
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available