L11F (p.Leu11Phe) variant of CDH1 (Cadherin-1)
L11F (p.Leu11Phe) in CDH1 (Cadherin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
L11F (p.Leu11Phe) variant details
- p.Leu11Phe
- gnomAD 19-3523017-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.07
- MetaLR 0.21
- MetaSVM -0.75
- CADD 22.70
- PolyPhen-2 0.04
- SIFT 0.11
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available
- Literature evidence available