Y64S (p.Tyr64Ser) variant of CDC42 (P60953)
Y64S (p.Tyr64Ser) in CDC42 (P60953) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as pathogenic in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes structural context.
Y64S (p.Tyr64Ser) variant details
- p.Tyr64Ser
- rs864309721
- ClinVar RCV004573105
- Pathogenic
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.783
- AlphaMissense 0.99
- MetaLR 0.81
- MetaSVM 0.80
- PolyPhen-2 1.00
- SIFT 0.00
- EVE 0.58
- ClinVar: Pathogenic (not provided)
- EBI: Pathogenic (in TKS)
- UniProt: Pathogenic (in TKS)
- Structural context available