T3S (p.Thr3Ser) variant of CDC42 (P60953)
T3S (p.Thr3Ser) in CDC42 (P60953) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
T3S (p.Thr3Ser) variant details
- p.Thr3Ser
- gnomAD 1-22078485-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.499
- CADD 21.90
- PolyPhen-2 0.02
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available
- Literature evidence available