S30L (p.Ser30Leu) variant of CDC42 (P60953)
S30L (p.Ser30Leu) in CDC42 (P60953) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
S30L (p.Ser30Leu) variant details
- p.Ser30Leu
- cosmic curated COSV59661
- Missense
- Variant Prioritization Score for Impact Estimate 0.734
- CADD 23.30
- PolyPhen-2 0.08
- SIFT 0.06
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available