R68* (p.Arg68Ter) variant of CDC42 (P60953)
R68* (p.Arg68Ter) in CDC42 (P60953) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
R68* (p.Arg68Ter) variant details
- p.Arg68Ter
- cosmic curated COSV59662
- gnomAD rs1645663269
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.859
- CADD 37.00
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available