R66T (p.Arg66Thr) variant of CDC42 (P60953)
R66T (p.Arg66Thr) in CDC42 (P60953) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data, published literature, and structural context.
R66T (p.Arg66Thr) variant details
- p.Arg66Thr
- rs763721408
- gnomAD 1-22078793-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.745
- CADD 17.50
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available
- Literature evidence available