D57Y (p.Asp57Tyr) variant of CDC42 (P60953)
D57Y (p.Asp57Tyr) in CDC42 (P60953) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
D57Y (p.Asp57Tyr) variant details
- p.Asp57Tyr
- NCI-TCGA Cosmic COSV1002
- cosmic curated COSV10021
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.83
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available