Y65C (p.Tyr65Cys) variant of CD80 (P33681)
Y65C (p.Tyr65Cys) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
Y65C (p.Tyr65Cys) variant details
- p.Tyr65Cys
- cosmic curated COSV10725
- Missense
- Variant Prioritization Score for Impact Estimate 0.634
- REVEL 0.70
- MetaLR 0.47
- MetaSVM 0.01
- CADD 27.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available