V73A (p.Val73Ala) variant of CD80 (P33681)
V73A (p.Val73Ala) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
V73A (p.Val73Ala) variant details
- p.Val73Ala
- gnomAD 3-119544750-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- REVEL 0.40
- MetaLR 0.33
- MetaSVM -0.26
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available