V45M (p.Val45Met) variant of CD80 (P33681)
V45M (p.Val45Met) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
V45M (p.Val45Met) variant details
- p.Val45Met
- cosmic curated COSV51802
- ExAC rs746220473
- gnomAD rs746220473
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.09
- MetaLR 0.13
- MetaSVM -0.97
- CADD 3.45
- PolyPhen-2 0.01
- SIFT 0.50
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available