V35A (p.Val35Ala) variant of CD80 (P33681)
V35A (p.Val35Ala) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
V35A (p.Val35Ala) variant details
- p.Val35Ala
- ESP rs142958721
- ExAC rs142958721
- TOPMed rs142958721
- gnomAD rs142958721
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.10
- MetaLR 0.03
- MetaSVM -1.06
- CADD 8.90
- PolyPhen-2 0.46
- SIFT 0.22
- Most common in the Ashkenazi Jewish population (allele frequency 0.0014)
- Structural context available