V24L (p.Val24Leu) variant of CD80 (P33681)
V24L (p.Val24Leu) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
V24L (p.Val24Leu) variant details
- p.Val24Leu
- 1000Genomes rs553548247
- ExAC rs553548247
- gnomAD rs553548247
- cosmic curated COSV51802
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.03
- MetaLR 0.03
- MetaSVM -0.95
- CADD 4.92
- PolyPhen-2 0.06
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available