S49Y (p.Ser49Tyr) variant of CD80 (P33681)
S49Y (p.Ser49Tyr) in CD80 (P33681) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
S49Y (p.Ser49Tyr) variant details
- p.Ser49Tyr
- gnomAD rs1285569312
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.41
- MetaLR 0.49
- MetaSVM -0.40
- CADD 25.30
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available